Mt 2:13-18
In the Old Testament, the tribes of Ephraim and Manasseh, descendants of Rachel, went into captivity and many people died. Their ancestor Rachel mourned the death of her descendants. (Jeremiah 31:15)
Jeremiah 31:15 Thus saith the Lord; A voice was heard in Ramah, lamentation, and bitter weeping; Rahel weeping for her children refused to be comforted for her children, because they were not.
As prophesied in the Old Testament, Jesus fled to Egypt to escape from Herod's threat. Herod killed all the boys under the age of two to kill Jesus, the Christ. This is the fulfillment of what Jeremiah prophesied. (Mt 2:13-18)
Mt 2:13 And when they were departed, behold, the angel of the Lord appeareth to Joseph in a dream, saying, Arise, and take the young child and his mother, and flee into Egypt, and be thou there until I bring thee word: for Herod will seek the young child to destroy him. 14 When he arose, he took the young child and his mother by night, and departed into Egypt: 15 And was there until the death of Herod: that it might be fulfilled which was spoken of the Lord by the prophet, saying, Out of Egypt have I called my son. 16 Then Herod, when he saw that he was mocked of the wise men, was exceeding wroth, and sent forth, and slew all the children that were in Bethlehem, and in all the coasts thereof, from two years old and under, according to the time which he had diligently inquired of the wise men. 17 Then was fulfilled that which was spoken by Jeremiah the prophet, saying, 18 In Rama was there a voice heard, lamentation, and weeping, and great mourning, Rachel weeping for her children, and would not be comforted, because they are not.